The challenge the vast number of permutations possible with the mixing and matching of jets/chokes/fuel levels/progression settings and holes/spill jet/pump jets etc etc. and you can do this for each cylinder!
Fuel level is set per pair of course and the pump jet but the rest are, to the best of my recollection, infinitely variable.
When I got mine, already on the car, they didn’t even have the same size auxiliary Venturi on each cylinder. For where the car was, St Louis, it was probably correct??
My biggest annoyance was the idle, just couldn’t get it nice and smooth. Once the car was rolling though it ran great but very rich.
Not sure how much I spent on parts and books but it was a lot. On my car the std solid throttle linkage didn’t operate very well with them either and I got it converted to cable. Much better!
If I had to do it again, and of course with hindsight, I’d find a specialist and ship it off to them to set it up, then never touch it again.
The std carbs in our cars are very forgiving, this is not the case with Webers, but when they are right, they are awesome……YMMV of course.
Bottom line, if you have the time/patience/money, go for it but find someone who has the parts/experience and equipment (read dyno) to set them up.
Might want to try someone in the classic car racing fraternity.
My carbs were 45DCOE. They had two progression holes, got it changed to three, that helped moving off from idle without a stumble.